Thermo-optically responsive hybrid hydrogel
4D-HTOR Hydrogel
Light-actuated scaffolds for dynamic mechanical stimulation and lung-model research.
| Composition | N-vinyl caprolactam (VCL), polyethylene glycol diacrylate (PEGDA) and functionalized gold nanorods (AuNRs) |
|---|---|
| Fabrication | High-resolution vat polymerization; LCD-printable resin |
| Actuation | 800 nm near-infrared irradiation produces AuNR-mediated photothermal stimulation |
| Response | Reversible VCL swelling–shrinkage |
| Reported deformation | Approximately 6% cyclic contraction–expansion |
| Representative geometry | 400 μm honeycomb cavities reproducing aspects of alveolar architecture |
| Surface functionalization | Polyarginine-functionalized AuNRs to enhance lung epithelial attachment |
| Biological response | Supports epithelial monolayers and mechanotransduction under dynamic stimulation |
| Ready-to-use format | Sterile 3 and 5 mL cartridges; compatibility with the selected bioprinter to be confirmed |
| Other formats | Powder for custom formulations; custom formats on request |
Catalogue evidence
Reported properties & results
- Catalogue describes honeycomb scaffolds with gradually decreasing pore sizes
- Reported thermoresponsive materials with tunable mechanical properties
- PEG-AuNR and PA/PEG-AuNR functionalization used to study genetic responses to mechanical and thermal stimuli
Results summarize the catalogue’s tested formulations and conditions. Confirm the protocol and formulation relevant to your experiment with MAKBY.
Technical catalogue
Source: October 2026 tissue engineering catalogue, printed page 18. Exact formulation, light dose or exposure time where applicable, storage duration and application-specific handling are available on enquiry.