Thermoresponsive poly(ether urethane) bioink
PoloxInk
Temperature-triggered gelation for extrusion bioprinting and payload delivery.
| Composition | P407-derived poly(ether urethane), CHP407/NHP407 |
|---|---|
| Gelation | Sol-to-gel transition on warming; concentration tunes gelation temperature and kinetics |
| Crosslinking | Temperature-triggered; no chemical crosslinkers, solvents, catalysts or UV curing required |
| Reported extrusion conditions | 15% w/v at 25 °C through G27 nozzles; 70–100 kPa |
| Reported gelation time | Less than 5 minutes at 37 °C |
| Fluid stability | Higher stability than corresponding native Poloxamer 407 formulations, as reported in the catalogue |
| Ready-to-use format | Sterile 3 and 5 mL cartridges; compatibility with the selected bioprinter to be confirmed |
| Other formats | Powder for custom formulations; custom formats on request |
Catalogue evidence
Reported properties & results
- Reported micellar cluster size: approximately 28–40 nm
- Reported cell viability above 80% across keratinocytes, myoblasts and fibroblasts
- FD4 diffusion reported as evidence of molecular transport through the matrix
Results summarize the catalogue’s tested formulations and conditions. Confirm the protocol and formulation relevant to your experiment with MAKBY.
Technical catalogue
Source: October 2026 tissue engineering catalogue, printed page 12. Exact formulation, light dose or exposure time where applicable, storage duration and application-specific handling are available on enquiry.