Parallel microfluidic screening platform

OmniEnzyme

Screen enzyme variants, bioink formulations and encapsulated payloads using microscale reactors and parallel analytical readouts.

Detailed specifications
Parallel measurements64 parallel readings
Plate compatibility384-well-compatible format
Fluid handlingNo pumps or valves required, according to the catalogue
InletChannel guides microparticles and active reagents into the reaction area
Reaction / detection architecturePhysical obstruction separates the primary reaction region from the downstream detection area
DetectionObservation window for analytical readouts
OutletChannel releases displaced air to support fluid flow
Enzyme retentionMicroscale packed-bed reactors with metal-affinity-functionalized microparticles retaining polyhistidine (His)-tagged enzymes
Screening variablesEnzyme variants, substrates, inhibitors, temperature and pH; bioink polymers, cells, crosslinkers, additives and processing conditions
Operating parametersExact working volumes, flow conditions, detection configuration and temperature/pH ranges are not specified in the catalogue; confirm for the selected experiment

Catalogue characterization & reported results

  • Catalogue reports 64 parallel measurements in a 384-well-compatible format
  • Metal-affinity microparticles retain His-tagged enzymes for reuse
  • Reuse over increasing reaction volumes and several months is reported for AldOTf, an alditol oxidase from Thermopolyspora flexuosa. Review the applicable conditions with MAKBY.

Technical catalogue

Specifications summarized from the October 2026 tissue engineering catalogue, printed page 20. Confirm the selected configuration, compatibility and experimental conditions with MAKBY.