In vitro and in vivo biomaterial studies
Pre-Clinical Biomaterials
Investigate biomaterial safety, tissue integration and functional performance through tailored preclinical studies.
| Test articles | 3D-bioprinted scaffolds, hydrogel patches, implantable regenerative constructs and bioengineered medical devices |
|---|---|
| Safety studies | Biocompatibility, toxicity, tolerance and immunological response |
| Functional endpoints | Tissue integration, neovascularization, mechanical stability, degradation kinetics and long-term implant function |
| Study services | In vitro and in vivo toxicity, dermal/ocular tolerance, pharmacodynamics, test-product administration and specimen procurement, as listed in the catalogue |
| Procedures | Laparoscopy, endoscopy, interventional radiology and microsurgery |
| Robotic-assisted surgery | Catalogue lists DA VINCI XI, SYMANI and VERSIUS systems |
| Imaging | Half-arc fluoroscopy, ultrasound and 3 Tesla MRI |
| Additional capabilities | 3D printing for prototyping and simulation |
| Model options | Catalogue lists rodents, lagomorphs, swine, sheep and canine models; selection depends on the study |
| Quality documentation | Catalogue reports GLP-certified services, ISO 9001:2015 quality and AAALAC-accredited animal care. Confirm the applicable facility, scope and current documentation with MAKBY. |
| Study specification | Endpoints, controls, sample numbers, observation periods and reporting scope are defined for the selected technology and development question |
Methods, deliverables & evidence
- Studies can evaluate tissue integration, vascularization, material degradation and functional performance
- Study findings can inform biomaterial design refinement
- Catalogue describes structured studies aligned with regulatory expectations; requirements and suitability must be reviewed for the particular technology
Technical catalogue
Specifications summarized from the October 2026 tissue engineering catalogue, printed page 26. Confirm the selected configuration, compatibility and experimental conditions with MAKBY.