Scaffold architecture and cell–matrix mapping
ScaffoldDynamics
Explore scaffold structure, temporal remodeling and cell–matrix interactions through multimodal microscopy.
| Platform | Proprietary laser-scanning nonlinear microscopy |
|---|---|
| Imaging modes | High-resolution label-free structural mapping and multi-channel fluorescence analysis |
| Structural analysis | Morphology, fiber organization, porosity and structural integrity of decellularized 3D-bioprinted scaffolds |
| Dynamic analysis | Temporal scaffold evolution, collagen-fiber orientation and remodeling |
| Living constructs | Cell distribution, viability and matrix interactions; structural integrity under dynamic conditions |
| Collagen imaging | Label-free second-harmonic generation (SHG) |
| 3D mapping | Z-stacks for cell distribution and penetration depth |
| Study parameters | Imaging volume, resolution, time points, sample preparation and quantitative deliverables are selected for the project; universal values are not given in the catalogue |
Methods, deliverables & evidence
- Catalogue illustrates fluorescence-labeled HUVECs/MSCs alongside label-free SHG collagen imaging
- Z-stacks reveal cell distribution and infiltration depth
- Reported comparisons at 3 and 10 days illustrate structural remodeling; composite collagen images integrate polarization states and z-planes
Technical catalogue
Specifications summarized from the October 2026 tissue engineering catalogue, printed page 24. Confirm the selected configuration, compatibility and experimental conditions with MAKBY.
